https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Multi-trait genome-wide association study identifies a novel endometrial cancer risk locus that associates with testosterone levels https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50960 Wed 28 Feb 2024 15:22:37 AEDT ]]> A graphical and computational modeling platform for biological pathways https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34906 Wed 22 May 2019 12:36:44 AEST ]]> Metabolic profiling from an asymptomatic ferret model of SARS-CoV-2 infection https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46928 Thu 08 Dec 2022 12:25:53 AEDT ]]> Evolving genetic networks for synthetic biology https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31580 Sat 24 Mar 2018 08:45:00 AEDT ]]> Outstanding issues in systems and synthetic biology https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:8516 Sat 24 Mar 2018 08:42:30 AEDT ]]> Systems and complexity thinking in the general practice literature: an integrative, historical narrative review https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21483 complex adaptive systems, nonlinear dynamics, systems biology, and systems theory, limited to general practice/family medicine and published before December 2010. A total of 16,242 articles were retrieved, of which 49 were published in general practice/family medicine journals. Hand searches and snowballing retrieved another 35. After a full-text review, we included 56 articles dealing specifically with systems sciences and general/family practice. Results: General practice/family medicine engaged with the emerging systems and complexity theories in 4 stages. Before 1995, articles tended to explore common phenomenologic general practice/family medicine experiences. Between 1995 and 2000, articles described the complex adaptive nature of this discipline. Those published between 2000 and 2005 focused on describing the system dynamics of medical practice. After 2005, articles increasingly applied the breadth of complex science theories to health care, health care reform, and the future of medicine. Conclusions: This historical review describes the development of general practice/family medicine in relation to complex adaptive systems theories, and shows how systems sciences more accurately reflect the discipline’s philosophy and identity. Analysis suggests that general practice/family medicine first embraced systems theories through conscious reorganization of its boundaries and scope, before applying empirical tools. Future research should concentrate on applying nonlinear dynamics and empirical modeling to patient care, and to organizing and developing local practices, engaging in community development, and influencing health care reform.]]> Sat 24 Mar 2018 08:03:35 AEDT ]]>